SOX2 REPRESSES HEPATITIS B VIRUS REPLICATION BY BINDING TO THE VIRAL ENHII/CP AND INHIBITING THE PROMOTER ACTIVATION

SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation

Hepatitis B virus (HBV) replication is controlled by four promoters (preS1, preS2, Cp, and Xp) and two enhancers (EnhI and EnhII).EnhII stimulates Cp activity to regulate the transcriptions of precore, core, polymerase, and pregenomic RNAs, and therefore, EnhII/Cp is essential for the regulation of HBV replication.This study revealed a distinct mec

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Evaluating classification tools for the prediction of in-vitro microbial pyruvate yield from organic carbon sources.

The laboratory-scale (in-vitro) microbial fermentation based on screening of process parameters (factors) Dog and statistical validation of parameters (responses) using regression analysis.The recent trends have shifted from full factorial design towards more complex response surface methodology designs such as Box-Behnken design, Central Composite

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